Diffuse Unpatterned Alopecia (DUPA)

When Hair Thins Everywhere – Even in the Donor Zone

DUPA is a form of androgenetic alopecia characterized by widespread hair thinning across the entire scalp, including the back and sides—areas typically unaffected by androgenetic alopecia. Because the so-called “safe donor zone” is also involved, this condition rules out hair transplant surgery for most patients.

Unlike patterned baldness, where hairline or crown thinning follows a recognizable pattern, DUPA has no clear pattern and affects even areas typically used for graft harvesting.

Key Takeaways

  • Affects the entire scalp, including donor zones
  • Not suitable for hair transplant surgery
  • Treatments like minoxidil, finasteride/dutasteride, PRP, or low level laser therapy may help slow progression and improve density.

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